@BotsRuinedEverything My opinion on games and mods is that the first playthrough should always be vanilla. This allows you to get a feel for what the game is actually like and allows you to provide an honest review for the game. It also lets you know what parts of the game need improvement so you know what mods to look for.

One thing I would suggest is to get the Phantom Liberty expansion. It fits really well with the rest of the game and adds a merchant to buy missed Iconic weapons.

@Cptn_Slow I’ve only immediately replayed two other games. Mass Effect and Dishonored.